Dr.Vipin Rana

Prof. Dr.Pradeep Kumar

Abstract

purpose:To present five cases of young Indian armed forces personnel who were posted at high altitude for a duration of at least six months and presented with central retinal artery occlusion.Methods: Optical coherence tomography, Fundus fluorescein angiography, Computed tomography angiography, hematological work up viz hemogram, serum erythropoietin level, anticardiolipin and antiβ2GPI antibodies, paroxysmal nocturnal hemoglobinuria assay by flow cytometry, serum homocysteine levels, JAK2 V617 F and JAK exon 12 mutation, lipid profile, 2D echocardiography and carotid doppler.
Results: The mean age was 34+/-4.2 years. All were male. Erythrocytosis was noticed in all patients, and two of them had hyperhomocysteinemia. Four out of five patients showed either common cerebral artery (CCA) or internal carotid artery (ICA) thrombosis on computed tomography angiography.