Dr. Radhika Kasilanka, Dr.Triveni Pottasiri , Dr.Pradeep Pakalapati

Abstract

STUDY DESIGN: Observational study
PURPOSE: To evaluate the effect of Anti-hypertensives on Systolic perfusion pressure (SPP), Diastolic perfusion pressure (DPP), Ocular perfusion pressure (OPP) and their association with progression of Primary Open Angle Glaucoma (POAG).
MATERIALS AND METHODS: Based on ICD-10, patients on Anti-hypertensives were divided into Early(n=15), Moderate(n=15) and Advanced(n=15) glaucoma and their SPP, DPP, OPP were assessed. Pearson correlation coefficient was used to measure their strength of linear association.
RESULTS: DPP, SPP and OPP were significantly lower in Advanced stages of glaucoma when compared to Early and Moderate stages.
CONCLUSION: Anti-hypertensives lowering the Perfusion pressures will have a detrimental effect on already compromised optic nerve head in Glaucoma patients